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Over two decades of open-source development for mass spectrometry workflows.
Expert-crafted ecosystem of computational mass spectrometry tools. Run scientifically vetted, cutting edge apps. Build custom tools on top of robust open-source algorithms. Join the OpenMS community.
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Over two decades of open-source development for mass spectrometry workflows.
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Peer-reviewed research citing OpenMS tools and algorithms worldwide.
Trusted and used by scientists worldwide.
Community tools
Apps are scientifically validated end-to-end solutions for common proteomics and metabolomics analysis. Test online, then download and deploy locally.
Web-based analysis and visualization of top-down proteomics data
View appInteractive DIA proteomics data analysis
View app
Web-based access to the umetaflow pipeline
View appWeb-based workflow for DDA proteomics
View app
Web-based access to the nucleic acid search engine (NASE)
View app
Web-based analysis pipeline for XL-MS data
View appWeb-based analysis pipeline for immunopeptidomics
View appEcosystem
Reusable C++ algorithms and data structures for mass spectrometry software. Ships with The OpenMS Pipeline (TOPP) command line tools for mass spectrometry analysis.
Python bindings to OpenMS-lib. Write custom analysis scripts and integrate OpenMS into Python workflows.
Web interface template for OpenMS pipelines. Deploy custom analysis tools as interactive web apps without frontend development.
Visualization library for mass spectrometry data. Create interactive and static plots directly from Python dataframes.
Community
OpenMS is built by a diverse group of contributors around the world. Whether you are new to mass spectrometry or a seasoned developer, there is a place for you in our community.
We are teaching a one-day workshop on MS analysis with OpenMS and OpenDIAKiosk at the University of Helsinki on April 30th 2026. Click the header above for more …
OpenMS announces Maria Llambrich Rodriguez as the 2026 Rising Star in Computational Mass Spectrometry recipient.
The OpenMS team applies as an organization for GSoC 2026 and invites the computational mass spectrometry community to join us in this effort.
We are teaching four two-day workshops in February 2026 in South Africa! Click the header above for more information.
Students collaborate with mentors on OpenMS features, documentation, and tool integrations.
Hands-on training on proteomics and metabolomics workflows with OpenMS and TOPP tools.
Annual developer meeting with tutorials, talks, and code sprints.
Contact
Tell us about your pipeline, integrations, or tooling goals — we will point you to the fastest next step.
Use the contact form for workflows, integrations, and support questions.
Contact usReach us directly at webmaster@openms.de for quick questions or routing help.
webmaster@openms.deInstallation guides, tutorials, and workflow documentation on Read the Docs.
Open docs